I finally decided that the primary difference between scanning a photo vs. negative on my Canon scanner is that with negatives there was an auxiliary light built into the cover that followed the scan. With that in mind I tried scanning negatives by placing them under a glass plate with a light above them. With a bright enough light it was *almost* possible to get a decent copy. After considerable trial and error I came up with the following, which works beautifully (IMHO).
I purchased two pieces of window glass that would just fit the glass in the scanner (for the Canon 8600 that is 8.5 x 11.5 inches). I used clear tape to fasten the glass plates together so that they could be opened like a book (I fastened the short side), and used a small piece of tape to create a tab that allowed me to easily lift the "negative holder" from the scanner. The bright light was easy--the sun! I removed the top from the Canon and placed it on a small table in direct sunlight. After experimenting for several days I found that a piece of translucent white plastic (salvaged from an old slide viewer) placed over the negative holder gave the best results with razor sharp scans.
I set the scanner to "Grayscale" and saved the images in TIFF format. Keep in mind that you probably will want to use a high resolution scan (I was using 800 dpi for most of my work). Using 800 dpi or higher will require a significant amount of memory and will require long scan times. I constructed a second negative holder so that I could load one while the other was scanning.
After scanning I used Photoshop to invert the negatives and rotate and crop them.
Below is the "raw scan" for a selection of negatives of different sizes and the final image for one of the images (this one was done at 600 dpi).
Happy scanning!